Anna Weinzinger: search on Z-Library

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1

Grayanotoxin Poisoning: ‘Mad Honey Disease’ and Beyond

Suze A. Jansen, Iris Kleerekooper, Zonne L. M. Hofman, Isabelle F. P. M. Kappen, Anna Stary-Weinzinger, Marcel A. G. van der Heyden

Journal:

Cardiovascular Toxicology

Year:

2012

Language:

english

File:

PDF, 293 KB

english, 2012

2

Glibenclamide and HMR1098 normalize Cantú syndrome‐associated gain‐of‐function currents

Houtman, Marien J. C., Chen, Xingyu, Qile, Muge, Duran, Karen, Haaften, Gijs, Stary‐Weinzinger, Anna, Heyden, Marcel A. G.

Journal:

Journal of Cellular and Molecular Medicine

Year:

2019

Language:

english

File:

PDF, 1.31 MB

english, 2019

3

Studying the Gating Mechanism of Mammalian Kir Channels using in Silico Mutations

Zangerl, Eva-Maria, Stary-Weinzinger, Anna

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 42 KB

english, 2015

4

Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels

Zangerl-Plessl, Eva-Maria, Lee, Sun-Joo, Maksaev, Grigory, Bernsteiner, Harald, Ren, Feifei, Yuan, Peng, Stary-Weinzinger, Anna, Nichols, Colin G.

Journal:

The Journal of General Physiology

Year:

2019

File:

PDF, 3.89 MB

2019

5

Pore Gating of K+ Channels Studied by Essential Dynamics Simulations using the Simplified Bacterial K+ Channel KcsA

Linder, Tobias, Stary-Weinzinger, Anna

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 39 KB

english, 2012

6

LUF7244 plus Dofetilide Rescues Aberrant K v 11.1 Trafficking and Produces Functional I Kv11.1

Qile, Muge, Ji, Yuan, Golden, Tyona D., Houtman, Marien J.C., Romunde, Fee, Fransen, Doreth, van Ham, Willem B., IJzerman, Ad P., January, Craig T., Heitman, Laura H., Stary-Weinzinger, Anna, Delisle,

Journal:

Molecular Pharmacology

Year:

2020

File:

PDF, 13.30 MB

2020

7

Dynamics of the EAG1 K+ channel selectivity filter assessed by molecular dynamics simulations

Bernsteiner, Harald, Bründl, Michael, Stary-Weinzinger, Anna

Journal:

Biochemical and Biophysical Research Communications

Year:

2017

Language:

english

File:

PDF, 1.50 MB

english, 2017

8

Timothy mutation affects tightly sealing point of CaV1.2 activation gate

Katrin Depil, Stanislav Beyl, Anna Stary-Weinzinger, Annette Hohaus, Eugen Timin, Steffen Hering

Journal:

BMC Pharmacology

Year:

2011

Language:

english

File:

PDF, 71 KB

english, 2011

9

A Novel Gating Mechanism of the NaVMs Selectivity Filter Suggested by Molecular Dynamics Simulations

Ke, Song, Stary-Weinzinger, Anna

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 46 KB

english, 2014

10

Investigating the Gating Mechanism of G Protein-Activated Inward Rectifying Potassium Channels

Bernsteiner, Harald, Stary-Weinzinger, Anna

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 45 KB

english, 2017

11

Computational Investigations of KATP Channel Pore Blockers

Chen, Xingyu, Zangerl-Plessl, Eva-Maria, Stary-Weinzinger, Anna

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 48 KB

english, 2017

12

Physicochemical Properties of Pore Residues Predict Activation Gating of Cav1.2: A Correlation Mutation Analysis

Depil, Katrin, Beyl, Stanislav, Hohaus, Annette, Stary-Weinzinger, Anna, Timin, Eugen, Shabbir, Waheed, Kudrnac, Michaela, Hering, Steffen

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 40 KB

english, 2011

13

PA-6 inhibits inward rectifier currents carried by V93I and D172N gain-of-function KIR2.1 channels, but increases channel protein expression

Ji, Yuan, Veldhuis, Marlieke G., Zandvoort, Jantien, Romunde, Fee L., Houtman, Marien J. C., Duran, Karen, van Haaften, Gijs, Zangerl-Plessl, Eva-Maria, Takanari, Hiroki, Stary-Weinzinger, Anna, van d

Journal:

Journal of Biomedical Science

Year:

2017

Language:

english

File:

PDF, 1.67 MB

english, 2017

14

Towards a structural view of hERG activation by the small molecule activator ICA-105574

Zangerl-Plessl, Eva-Maria, Berger, Martin, Drescher, Martina, Chen, Yong, Wu, Wei, Maulide, Nuno, Sanguinetti, Michael, Stary-Weinzinger, Anna

Journal:

Journal of Chemical Information and Modeling

Year:

2019

File:

PDF, 3.92 MB

2019

15

Neutralizing the Charges in a Voltage Sensor Repairs Gating Perturbations in the Pore of CaV1.2

Beyl, Stanislav, Depil, Katrin, Hohaus, Annette, Stary-Weinzinger, Anna, Timin, Eugen, Hering, Steffen

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 62 KB

english, 2012

16

ICA105574 Binds to a Similar Region of the Pore Domain to Induce Opposite Effects on the Gating of EAG and ERG Channels

Garg, Vivek, Stary-Weinzinger, Anna, Sanguinetti, Michael C.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 65 KB

english, 2012

17

Drug Trapping in hERG Channels does not Require Closure of the Activation Gate

Saxena, Priyanka, Erker, Thomas, Bauer, Florian, Stary-Weinzinger, Anna, Linder, Tobias, Hering, Steffen, Timin, Eugen

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 41 KB

english, 2013

18

Conserved functional consequences of disease-associated mutations in the slide-helix of Kir6.1 and Kir6.2 subunits of the ATP-sensitive potassium channel

Cooper, Paige E, McClenaghan, Conor, Chen, Xingyu, Stary-Weinzinger, Anna, Nichols, Colin G.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 1.26 MB

english, 2017

19

Cysteines in the loop between IS5 and the pore helix of CaV3.1 are essential for channel gating

Maria Karmazinova, Stanislav Beyl, Anna Stary-Weinzinger, Chonticha Suwattanasophon, Norbert Klugbauer, Steffen Hering, Lubica Lacinova

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2010

Language:

english

File:

PDF, 629 KB

english, 2010

20

MD Simulations of KirBac1.1 Mutants Reveal Gating Changes at the Bundle Crossing Region

Weinzinger, Anna

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 33 KB

english, 2013

21

Exploring the Structure of the Voltage-gated Na + Channel by an Engineered Drug Access Pathway to the Receptor Site for Local Anesthetics

Lukacs, Peter, Gawali, Vaibhavkumar S., Cervenka, Rene, Ke, Song, Koenig, Xaver, Rubi, Lena, Zarrabi, Touran, Hilber, Karlheinz, Stary-Weinzinger, Anna, Todt, Hannes

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.09 MB

english, 2014

22

Histidine at position 462 determines the low quinine sensitivity of ether‐à‐go‐go (Eag) channel superfamily member K v 12.1

Dierich, Marlen, Ham, Willem B., Stary‐Weinzinger, Anna, Leitner, Michael G.

Journal:

British Journal of Pharmacology

Year:

2019

Language:

english

File:

PDF, 13.01 MB

english, 2019

23

Insights into Molecular Basis of hERG Inhibition by Studying a Library of Dofetilide Derivatives

Saxena, Priyanka, Linder, Tobias, Stary-Weinzinger, Anna, IJzerman, Adriaan P., Timin, Eugen, Franz Ecker, Gerhard, Hering, Steffen

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 45 KB

english, 2014

24

Activation Gating of KcsA: New Insights into Cooperativity and Energy Landscape from Essential Dynamics Simulations

Linder, Tobias, Stary-Weinzinger, Anna

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 56 KB

english, 2013

25

Insights in KIR2.1 channel structure and function by an evolutionary approach; cloning and functional characterization of the first reptilian inward rectifier channel KIR2.1, derived from the California kingsnake (Lampropeltis getula californiae)

Houtman, Marien J.C., Korte, Sanne M., Ji, Yuan, Kok, Bart, Vos, Marc A., Stary-Weinzinger, Anna, van der Heyden, Marcel A.G.

Journal:

Biochemical and Biophysical Research Communications

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

26

Drug trapping in hERG K + channels: (not) a matter of drug size?

Linder, Tobias, Bernsteiner, Harald, Saxena, Priyanka, Bauer, Florian, Erker, Thomas, Timin, Eugen, Hering, Steffen, Stary-Weinzinger, Anna

Journal:

Year:

2016

Language:

english

File:

PDF, 2.25 MB

english, 2016

27

Conduction and Selectivity in Kir3.2 Channels - A Molecular Dynamics Study

Stary-Weinzinger, Anna, Bernsteiner, Harald

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 45 KB

2020

28

Towards a Structural Understanding of Cantú Disease Associated Gating Perturbations in the KATP Potassium Channel

Plessl, Eva-Maria, Stary-Weinzinger, Anna

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 58 KB

english, 2016

29

Distinct modulation of inactivation by a residue in the pore domain of voltage-gated Na+ channels: mechanistic insights from recent crystal structures

Cervenka, Rene, Lukacs, Peter, Gawali, Vaibhavkumar S., Ke, Song, Koenig, Xaver, Rubi, Lena, Zarrabi, Touran, Hilber, Karlheinz, Sandtner, Walter, Stary-Weinzinger, Anna, Todt, Hannes

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.11 MB

english, 2018

30

Computational Insights into Atomistic Details of Na+ Versus Ca2+ Discrimination in Sodium Channel NavAb

Ke, Song, Stary-Weinzinger, Anna

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 36 KB

english, 2013

31

Mutational Analysis in the Bundle Crossing Region Guides the Design of Cav1.2 Homology Models

Weinzinger, Anna, Depil, Katrin, Beyl, Stanislav, Timin, Eugen, Hering, Steffen

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 40 KB

english, 2011

32

Different Inward and Outward Conduction Mechanisms in NaVMs Suggested by Molecular Dynamics Simulations

Ke, Song, Timin, E. N., Stary-Weinzinger, Anna, Tajkhorshid, Emad

Journal:

PLoS Computational Biology

Year:

2014

Language:

english

File:

PDF, 3.95 MB

english, 2014

33

Computational Insights into Voltage Dependence of Polyamine Block in Inwardly Rectifying K+ Channels

BrÃ¼ndl, Michael, Chen, Xingyu, Stary-Weinzinger, Anna

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 43 KB

2020

34

Conformational Flexibility of the hERG K+ Channel Pore Domain

Weinzinger, Anna, Knape, Kirsten, Wacker, Sören J., Boukharta, Lars, de Groot, Bert L.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 36 KB

english, 2010

35

Surprises from an Unusual CLC Homolog

Phillips, Sabrina, Brammer, Ashley E., Rodriguez, Luis, Lim, Hyun-Ho, Stary-Weinzinger, Anna, Matulef, Kimberly

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 244 KB

english, 2012

36

Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa , are I Kr blockers with proarrhythmic effects in vitro and in vivo

Baburin, Igor, Varkevisser, Rosanne, Schramm, Anja, Saxena, Priyanka, Beyl, Stanislav, Szkokan, Phillip, Linder, Tobias, Stary-Weinzinger, Anna, van der Heyden, Marcel A.G., Houtman, Marien, Takanari,

Journal:

Pharmacological Research

Year:

2018

Language:

english

File:

PDF, 4.42 MB

english, 2018

37

Inactivation Properties, not Binding Site Differences, Govern Reciprocal Functional Response to ICA105574 in EAG and ERG Potassium Channels

Garg, Vivek, Stary-Weinzinger, Anna, Sanguinetti, Michael C.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 41 KB

english, 2013

38

Molecular Dynamics Simulations of KirBac1.1 Mutants Reveal Global Gating Changes of Kir Channels

Linder, Tobias, Wang, Shizhen, Zangerl-Plessl, Eva-Maria, Nichols, Colin G., Stary-Weinzinger, Anna

Journal:

Journal of Chemical Information and Modeling

Year:

2015

Language:

english

File:

PDF, 529 KB

english, 2015

39

A structural model of the human serotonin transporter in an outward-occluded state

Hellsberg, Eva, Ecker, Gerhard F., Stary-Weinzinger, Anna, Forrest, Lucy R., Soares, Claudio M.

Journal:

Year:

2019

Language:

english

File:

PDF, 3.00 MB

english, 2019

40

Disease Associated Mutations in KIR Proteins Linked to Aberrant Inward Rectifier Channel Trafficking

Zangerl-Plessl, Eva-Maria, Qile, Muge, Bloothooft, Meye, Stary-Weinzinger, Anna, van der Heyden, Marcel A. G.

Journal:

Year:

2019

Language:

english

File:

PDF, 2.00 MB

english, 2019

41

Towards a structural view of hERG activation by the small molecule activator ICA-105574

Zangerl-Plessl, Eva-Maria, Berger, Martin, Drescher, Martina, Chen, Yong, Wu, Wei, Maulide, Nuno, Sanguinetti, Michael, Stary-Weinzinger, Anna

Journal:

Journal of Chemical Information and Modeling

Year:

2019

Language:

english

File:

PDF, 3.92 MB

english, 2019

42

Distinct interactions of Na+ and Ca2+ ions with the selectivity filter of the bacterial sodium channel NaVAb

Ke, Song, Zangerl, Eva-Maria, Stary-Weinzinger, Anna

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 769 KB

english, 2013

43

Computer Simulations of Structure–Activity Relationships for hERG Channel Blockers

Boukharta, Lars, Keränen, Henrik, Stary-Weinzinger, Anna, Wallin, Göran, de Groot, Bert L., Åqvist, Johan

Journal:

Year:

2011

Language:

english

File:

PDF, 3.29 MB

english, 2011

44

Computational Insights Into Voltage Dependence of Polyamine Block in a Strong Inwardly Rectifying K+ Channel

Chen, Xingyu, BrÃ¼ndl, Michael, Friesacher, Theres, Stary-Weinzinger, Anna

Journal:

Frontiers in Pharmacology

Year:

2020

File:

PDF, 2.63 MB

2020

45

Physicochemical properties of pore residues predict activation gating of CaV1.2: A correlation mutation analysis

Stanislav Beyl, Katrin Depil, Annette Hohaus, Anna Stary-Weinzinger, Eugen Timin, Waheed Shabbir, Michaela Kudrnac, Steffen Hering

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2011

Language:

english

File:

PDF, 370 KB

english, 2011

46

Selectivity Profiling of the Human Monoamine Transporters: Investigation of the Serotonin Transporter Mechanism

Hellsberg, Eva, Forrest, Lucy R., Stary-Weinzinger, Anna, Ecker, Gerhard F.

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 45 KB

english, 2018

47

Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids

Lee, Sun-Joo, Ren, Feifei, Zangerl-Plessl, Eva-Maria, Heyman, Sarah, Stary-Weinzinger, Anna, Yuan, Peng, Nichols, Colin G.

Journal:

The Journal of General Physiology

Year:

2016

Language:

english

File:

PDF, 2.39 MB

english, 2016

48

Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole

Gualdani, Roberta, Cavalluzzi, Maria Maddalena, Tadini-Buoninsegni, Francesco, Convertino, Marino, Gailly, Philippe, Stary-Weinzinger, Anna, Lentini, Giovanni

Journal:

Cellular Physiology and Biochemistry

Year:

2018

Language:

english

File:

PDF, 1.98 MB

english, 2018

49

Conduction through a narrow inward-rectifier K + channel pore

Bernsteiner, Harald, Zangerl-Plessl, Eva-Maria, Chen, Xingyu, Stary-Weinzinger, Anna

Journal:

The Journal of General Physiology

Year:

2019

Language:

english

File:

PDF, 2.65 MB

english, 2019

50

Structural Insights into Trapping and Dissociation of Small Molecules in K + Channels

Linder, Tobias, Saxena, Priyanka, Timin, Eugen, Hering, Steffen, Stary-Weinzinger, Anna

Journal:

Journal of Chemical Information and Modeling

Year:

2014

Language:

english

File:

PDF, 4.06 MB

english, 2014

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